Research Studies

Published research on HBOT for Autism Spectrum Disorder

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These publications include different levels of evidence—not necessarily clinical trials. PubMed indexing is not proof of benefit or an endorsement. Summaries are based on available PubMed abstracts, not a formal full-text quality assessment. Read the limitations as well as the findings; some papers report no benefit or potential harms.

Systematic review 2016

Hyperbaric oxygen therapy for people with autism spectrum disorder (ASD). (opens PubMed in a new tab)

Xiong T; Chen H; Luo R; Mu D — The Cochrane database of systematic reviews

Plain English Summary

This Cochrane review found no evidence that HBOT improved core or associated autism symptoms in the eligible trial.

Limitations & context: Evidence quality was low, and ear barotrauma and other adverse events occurred. PubMed indexing is not an endorsement of treatment.

View on PubMed · PMID 27737490

Randomized open-label trial 2022

Effect of hyperbaric oxygen therapy and Tomatis sound therapy in children with autism spectrum disorder. (opens PubMed in a new tab)

El-Tellawy MM; Ahmad AR; Saad K; Alruwaili TAM; AbdelMoneim IM; Shaaban I; Alinad AKM; Albulayhid SBH; Khalaf SM — Progress in neuro-psychopharmacology & biological psychiatry

Plain English Summary

An open-label study compared HBOT, Tomatis sound therapy, their combination, and no intervention in children with autism; the combined treatment showed improvement.

Limitations & context: The absence of blinding and the combined intervention limit conclusions about HBOT itself. The authors describe the evidence as controversial.

View on PubMed · PMID 34662695

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before starting HBOT or any treatment. Individual results may vary.