Research Studies

Published research on HBOT for Carbon Monoxide Poisoning

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These publications include different levels of evidence—not necessarily clinical trials. PubMed indexing is not proof of benefit or an endorsement. Summaries are based on available PubMed abstracts, not a formal full-text quality assessment. Read the limitations as well as the findings; some papers report no benefit or potential harms.
Randomized controlled trial 2002

Hyperbaric oxygen for acute carbon monoxide poisoning. (opens PubMed in a new tab)

Weaver LK; Hopkins RO; Chan KJ; Churchill S; Elliott CG; Clemmer TP; Orme JF; Thomas FO; Morris AH — The New England journal of medicine

Plain English Summary

This blinded trial found fewer cognitive complications after acute carbon monoxide poisoning in the HBOT group than in the comparison group.

Limitations & context: The trial stopped early for benefit. Other trials have not consistently reproduced the findings; read alongside the systematic review.

View on PubMed · PMID 12362006
Randomized controlled trial 1995

Delayed neuropsychologic sequelae after carbon monoxide poisoning: prevention by treatment with hyperbaric oxygen. (opens PubMed in a new tab)

Thom SR; Taber RL; Mendiguren II; Clark JM; Hardy KR; Fisher AB — Annals of emergency medicine

Plain English Summary

In this randomized trial of mild to moderate carbon monoxide poisoning, no delayed neurological complications developed in 30 patients treated with HBOT, compared with 7 of 30 patients (23%) given 100% oxygen at normal pressure. The authors concluded that early HBOT reduced these complications in the patients studied.

Limitations & context: Small trial with 30 patients per group. Participants presented within 6 hours and had no history of loss of consciousness or cardiac instability, so the results do not establish effectiveness in all poisoning cases. Other trials have reported conflicting results; this positive study alone does not settle the overall evidence. Carbon monoxide poisoning requires emergency medical assessment and treatment.

View on PubMed · PMID 7710151

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before starting HBOT or any treatment. Individual results may vary.