Research Studies

Published research on HBOT for Chronic Pain Syndromes

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These publications include different levels of evidence—not necessarily clinical trials. PubMed indexing is not proof of benefit or an endorsement. Summaries are based on available PubMed abstracts, not a formal full-text quality assessment. Read the limitations as well as the findings; some papers report no benefit or potential harms.

Randomized placebo-controlled trial 2004

Effectiveness of hyperbaric oxygen therapy in the treatment of complex regional pain syndrome. (opens PubMed in a new tab)

Kiralp MZ; Yildiz S; Vural D; Keskin I; Ay H; Dursun H — The Journal of international medical research

Plain English Summary

People with complex regional pain syndrome had improvements in pain, swelling, and most measured wrist movements after HBOT compared with control treatment.

Limitations & context: This study concerns a specific regional pain syndrome and short-term outcomes, not all chronic pain conditions.

View on PubMed · PMID 15174218

Retrospective case series 2024

The Effectiveness of Hyperbaric Oxygen Treatment in Patients with Complex Regional Pain Syndrome: A Retrospective Case series. (opens PubMed in a new tab)

Hájek M; Chmelař D; Tlapák J; Klugar M — International journal of medical sciences

Plain English Summary

Many patients with complex regional pain syndrome reported improved pain and limb function after a course of HBOT.

Limitations & context: Without a randomized comparison group, the series cannot separate HBOT effects from other care or natural recovery.

View on PubMed · PMID 39239556

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before starting HBOT or any treatment. Individual results may vary.