Research Studies

Published research on HBOT for Compromised Grafts and Flaps

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These publications include different levels of evidence—not necessarily clinical trials. PubMed indexing is not proof of benefit or an endorsement. Summaries are based on available PubMed abstracts, not a formal full-text quality assessment. Read the limitations as well as the findings; some papers report no benefit or potential harms.

Clinical and preclinical review 2017

Hyperbaric Oxygen Therapy for the Compromised Graft or Flap. (opens PubMed in a new tab)

Francis A; Baynosa RC — Advances in wound care

Plain English Summary

Reviews HBOT as a possible salvage treatment for compromised skin grafts and flaps and discusses proposed mechanisms.

Limitations & context: Much clinical evidence consists of case reports and series. The review concerns compromised tissue, not routine use for healthy grafts.

View on PubMed · PMID 28116225

Retrospective case series 2021

Hyperbaric oxygen treatment for mastectomy flap ischaemia: A case series of 50 breasts. (opens PubMed in a new tab)

Spruijt NE; Hoekstra LT; Wilmink J; Hoogbergen MM — Diving and hyperbaric medicine

Plain English Summary

Reports outcomes for ischemic mastectomy flaps treated with HBOT. Some breasts recovered without further surgery, while others required reoperation.

Limitations & context: There was no randomized comparison group. The authors call for a controlled trial to determine whether HBOT improves outcomes.

View on PubMed · PMID 33761535

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before starting HBOT or any treatment. Individual results may vary.