Research Studies

Published research on HBOT for Crush Injuries

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These publications include different levels of evidence—not necessarily clinical trials. PubMed indexing is not proof of benefit or an endorsement. Summaries are based on available PubMed abstracts, not a formal full-text quality assessment. Read the limitations as well as the findings; some papers report no benefit or potential harms.
Randomized controlled trial 2022

Hyperbaric Oxygen for Lower Limb Trauma (HOLLT): an international multi-centre randomised clinical trial. (opens PubMed in a new tab)

Millar IL; Lind FG; Jansson KÅ; Hájek M; Smart DR; Fernandes TD; McGinnes RA; Williamson OD; Miller RK; Martin CA; Gabbe BJ; Myles PS; Cameron PA; HOLLT investigator group — Diving and hyperbaric medicine

Plain English Summary

In severe lower-limb trauma, the combined primary outcome of infection or necrosis was not significantly reduced. Tissue necrosis and some later complications were lower with HBOT.

Limitations & context: The study involved open tibial fractures and severe soft-tissue trauma. Secondary benefits should be interpreted alongside the nonsignificant primary outcome.

View on PubMed · PMID 36100927
Retrospective comparative study 2024

The use of hyperbaric oxygen therapy in the treatment of hand crush injuries. (opens PubMed in a new tab)

Chang DH; Hsieh CY; Chang CW; Wang HH; Chang HT — Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society

Plain English Summary

Patients with hand crush injuries were compared with and without HBOT. Some subgroups had shorter healing times or hospital stays.

Limitations & context: Treatment groups differed in injury size, and several outcomes were not statistically significant. Randomized studies are needed.

View on PubMed · PMID 38129180

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before starting HBOT or any treatment. Individual results may vary.