Research Studies

Published research on HBOT for Intracranial Abscess

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These publications include different levels of evidence—not necessarily clinical trials. PubMed indexing is not proof of benefit or an endorsement. Summaries are based on available PubMed abstracts, not a formal full-text quality assessment. Read the limitations as well as the findings; some papers report no benefit or potential harms.

Comparative cohort study 2016

Hyperbaric oxygen therapy in spontaneous brain abscess patients: a population-based comparative cohort study. (opens PubMed in a new tab)

Bartek J; Jakola AS; Skyrman S; Förander P; Alpkvist P; Schechtmann G; Glimåker M; Larsson A; Lind F; Mathiesen T — Acta neurochirurgica

Plain English Summary

Brain abscess patients receiving HBOT alongside surgery and antibiotics had fewer treatment failures and reoperations and better reported long-term outcomes.

Limitations & context: Treatment was not randomized. The authors recommend prospective studies to establish HBOT's role.

View on PubMed · PMID 27113742

Retrospective comparative study 2025

Hyperbaric oxygen therapy for brain abscesses: A useful adjuvant treatment for a faster recovery. (opens PubMed in a new tab)

Brunner A; Lindenmann J; Pistracher K; Micko A; Pichler A; Enzinger C; Smolle-Jüttner F; Wolfsberger S; Kurschel-Lackner S — Neurosurgical review

Plain English Summary

Patients receiving adjunctive HBOT for brain abscesses had better radiological resolution and neurological outcomes at reported follow-up points.

Limitations & context: Observational group differences can affect the results. HBOT was added to antimicrobial and neurosurgical treatment.

View on PubMed · PMID 40731157

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before starting HBOT or any treatment. Individual results may vary.