Research Studies

Published research on HBOT for Migraine

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These publications include different levels of evidence—not necessarily clinical trials. PubMed indexing is not proof of benefit or an endorsement. Summaries are based on available PubMed abstracts, not a formal full-text quality assessment. Read the limitations as well as the findings; some papers report no benefit or potential harms.

Systematic review / meta-analysis 2015

Normobaric and hyperbaric oxygen therapy for the treatment and prevention of migraine and cluster headache. (opens PubMed in a new tab)

Bennett MH; French C; Schnabel A; Wasiak J; Kranke P; Weibel S — The Cochrane database of systematic reviews

Plain English Summary

The review found low-certainty evidence for relief of acute migraine with HBOT, but no evidence that it prevents migraine episodes.

Limitations & context: The review also covers normobaric oxygen for cluster headache, which is a different treatment and condition. These findings must not be conflated.

View on PubMed · PMID 26709672

Randomized clinical trial 1998

Hyperbaric oxygen in the treatment of migraine with aura. (opens PubMed in a new tab)

Wilson JR; Foresman BH; Gamber RG; Wright T — Headache

Plain English Summary

Women with migraine reported less subjective headache pain after hyperbaric oxygen than after oxygen without increased pressure.

Limitations & context: The study concerns acute migraine relief, not proven prevention. Other measured tenderness outcomes did not show the same difference.

View on PubMed · PMID 9529766

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before starting HBOT or any treatment. Individual results may vary.