Research Studies

Published research on HBOT for Spinal Cord Injury

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These publications include different levels of evidence—not necessarily clinical trials. PubMed indexing is not proof of benefit or an endorsement. Summaries are based on available PubMed abstracts, not a formal full-text quality assessment. Read the limitations as well as the findings; some papers report no benefit or potential harms.

Systematic review / meta-analysis 2021

Effects of hyperbaric oxygen therapy on patients with spinal cord injury: A systematic review and meta-analysis of Randomized Controlled Trials. (opens PubMed in a new tab)

Huang L; Zhang Q; Fu C; Liang Z; Xiong F; He C; Wei Q — Journal of back and musculoskeletal rehabilitation

Plain English Summary

Pooled trials suggested improvements in motor, sensory, and psychological measures after spinal cord injury with adjunctive HBOT.

Limitations & context: Several outcomes varied substantially between studies. The authors call for larger, higher-quality randomized trials.

View on PubMed · PMID 33935063

Randomized clinical trial 2019

Effect of hyperbaric oxygen therapy on HMGB1/NF-κB expression and prognosis of acute spinal cord injury: A randomized clinical trial. (opens PubMed in a new tab)

Sun L; Zhao L; Li P; Liu X; Liang F; Jiang Y; Kang N; Gao C; Yang J — Neuroscience letters

Plain English Summary

Patients with acute spinal cord injury receiving HBOT plus conventional care showed improvements in short-term neurological scores and inflammatory markers.

Limitations & context: Short-term clinical and biomarker changes do not establish durable recovery or effectiveness for longstanding spinal cord injuries.

View on PubMed · PMID 30391318

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before starting HBOT or any treatment. Individual results may vary.