Research Studies

Published research on HBOT for Stroke Recovery

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These publications include different levels of evidence—not necessarily clinical trials. PubMed indexing is not proof of benefit or an endorsement. Summaries are based on available PubMed abstracts, not a formal full-text quality assessment. Read the limitations as well as the findings; some papers report no benefit or potential harms.

Randomized crossover trial 2013

Hyperbaric oxygen induces late neuroplasticity in post stroke patients--randomized, prospective trial. (opens PubMed in a new tab)

Efrati S; Fishlev G; Bechor Y; Volkov O; Bergan J; Kliakhandler K; Kamiager I; Gal N; Friedman M; Ben-Jacob E; Golan H — PloS one

Plain English Summary

Patients with chronic post-stroke deficits improved on neurological and quality-of-life measures after HBOT compared with a no-treatment observation period.

Limitations & context: The study lacked a sham chamber control. Expectations and other nonspecific effects cannot be excluded.

View on PubMed · PMID 23335971

Randomized trial 2024

Hyperbaric Oxygen Post Established Stroke. (opens PubMed in a new tab)

Harrison DW; Brasher PM; Eng JJ; Harris D; Hoens AM; Khazei A; Yao JK; Abu-Laban RB — Cureus

Plain English Summary

This trial in chronic stroke survivors did not find a clinically important HBOT benefit on the primary Stroke Impact Scale outcome; the sham group performed better.

Limitations & context: Recruitment was low and the control design changed during the study. The findings contrast with earlier positive uncontrolled or unblinded evidence.

View on PubMed · PMID 39070389

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before starting HBOT or any treatment. Individual results may vary.